Liliana Brambilla
Biologo

Contatta il professionista

Guidotti G, Brambilla L, Rossi D. Cell-Penetrating Peptides: from basic research to clinics. Trends Pharmacol Sci.2017Apr;38(4):406-424.doi:10.1016/j.tips.2017.01.003. Epub 2017 Feb 14.

Brambilla L, Guidotti G, Martorana F, Iyer AM, Aronica E, Valori CF, Rossi D. Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis. Hum Mol Genet. 2016 Jun 15:25(14):3080-3095. Epub 2016 Jun 10.

Martorana F, Guidotti G, Brambilla L and Rossi D. Withaferin A inhibits nuclear factor-kappaB-dependent proinflammatory and stress response pathways in the astrocytes. Neural Plasticity, 2015:381964. doi: 10.1155/2015/381964. Epub 2015 Jul 21.

Valori CF, Brambilla L, Martorana F and Rossi D. The multifaceted role of glial cells in amyotrophic lateral sclerosis. Cellular Molecular Life Sciences, 2014, 71(2): 287-297.

Brambilla L, Martorana F and Rossi, D. Astrocyte Signalling and Neurodegeneration: new Insights into CNS Disorders. Prion, 2013, 7(1):28-36.

Benedusi V, Martorana F, Brambilla L, Maggi A and Rossi D. The Peroxisome Proliferator-Activated Receptor (PPAR) controls natural protective mechanisms against lipid peroxidation in Amyotrophic Lateral Sclerosis. Journal of Biological Chemistry, 2012, 19;287(43):35899-35911.

Martorana F, Brambilla L, Valori CF, Bergamaschi C, Roncoroni C, Aronica E, Volterra A, Bezzi P and Rossi D. The BH4 domain of Bcl-XL rescues astrocyte de generation in Amiotrophic Lateral Sclerosis by modulating intracellular calcium signals. Human Molecular Genetics, 2012, 21(4): 826-840.

Rossi D, Martorana F and Brambilla L. Implications of Gliotrasmission for the Pharmacotherapy of CNS Disorders. CNS Drugs, 2011, 25(8): 641-658.

Rossi D, Brambilla L, Valori CF, Crugnola A, Roncoroni C, Yokota T, Bredesen D and Volterra A. Focal degeneration of astrocytes in amyotrophic lateral slerosis. Cell Death & Differentiation, 2008, 15(11): 1691-1700.

Rossi D*, Brambilla L*, Valori CF, Crugnola A, Giaccone G, Capobianco R, Mangieri M, Kingston AE, Bloc A, Bezzi P and Volterra A.  Defective TNF-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer’s disease. The Journal of Biological Chemistry, 2005, 280(51), 42088-42096.

Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, Vescovi A, Bagetta G, Kollias G, Meldolesi J and Volterra A.  CXCR4-activated astrocyte glutamate release via TNF: amplification by microglia triggers neurotoxicity.  Nature Neuroscience 2001, 4, 702-710.

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